Introduction to Medical Cannabis: The Evidence Base
This evidence summary provides a clear, accessible introduction to the scientific and clinical foundations of medical cannabis. At a time when understanding is evolving rapidly, this publication offers a direct, evidence-based overview that educates, informs and supports better decision-making in an emerging area of medicine.
Designed for clinicians, educators and healthcare professionals, it brings together core research, historical context and regulatory information. It also serves as a valuable reference for patients and interested readers seeking clarity in a field often shaped by misinformation and uncertainty. This introductory volume forms the foundation for the wider MCCS Evidence Base Series.
The publication examines the history of medical cannabis, the endocannabinoid system, product types, manufacturing standards and the UK legal landscape. It reviews scientific evidence, real-world data, safety considerations, drug interactions and key factors influencing treatment response.
With more than 280 referenced studies, it offers a comprehensive starting point for further reading and clinical exploration.
Content includes:
- History of medical cannabis and its development into a modern therapy
- The endocannabinoid system and its relevance to clinical care
- Composition of the cannabis plant, including cannabinoids, terpenes and chemovars
- Medical cannabis products, formulation types and production standards
- Evidence base for prescription and patient demographics
- UK legal and regulatory framework
- Safety profile, cautions, dependency considerations and potential risks
- Precautions and contraindications
- Overview of prescribing pathways and practical considerations
- Extensive reference list for deeper study
Format: Digital PDF
Length: 64 pages
Authors: Prof Mike Barnes & Hannah Deacon
Publisher: Medical Cannabis Clinicians Society (2025)
FAQ
Who is this evidence summary for?
It is written for healthcare professionals seeking a clear, research-based introduction to the scientific and regulatory foundations of medical cannabis. It is also suitable for patients and general readers who want an informed overview.
Does this publication include prescribing advice?
No. It provides scientific, historical and regulatory context. Practical prescribing guidance is covered in Medical Cannabis Oils: Dosing and Guidance for Safe and Effective Treatment in Adults and Children, also available in this bookshop.
What topics are included?
The publication covers the history of medical cannabis, the endocannabinoid system, plant chemistry, chemovars, formulation types, evidence for prescribing, real-world data, safety considerations, drug interactions, and UK regulatory requirements.
Is the content independent?
Yes. It is produced by the Medical Cannabis Clinicians Society and is based on published research, expert clinical insight and current UK guidance.